FIG. 4.

Colonization and dissemination of PAK in a mouse acute pneumonia model are attenuated in strains lacking exoS. Mice were inoculated intranasally with 5 × 10⁷ CFU of PAK or derivatives. At 16 h postinfection, the lungs (A), 300 mg of livers (B; gray bars), and spleens (B; white bars) were harvested and the number of CFU of P. aeruginosa was determined by serial dilution and plating on L agar. Error bars indicate standard deviations.