TABLE 2.
Peripheral blood counts in untreated and immune-depleted mice
| Cell type | Blood count (cells/mm3) ± SD in C57BL/6 mice
|
||
|---|---|---|---|
| Untreated (n = 4) | Treated with:
|
||
| Cyclophosphamide (200 mg/kg) (n = 4) | Cyclophosphamide and RB6 (250 μg) (n = 4) | ||
| Total white blood cells | (10.6 ± 0.4) × 103 | (0.17 ± 0.10) × 103 | (0.04 ± 0.02) × 103 |
| Red blood cells | (9.6 ± 0.4) × 106 | (6.65 ± 0.08) × 106 | (9.5 ± 2.4) × 106 |
| Neutrophils | (0.8 ± 0.0) × 103 | (0.06 ± 0.05) × 103 | (0.005 ± 0.01) × 103 (undetected in 3 of 4 mice) |
| Lymphocytes | (9.4 ± 0.4) × 103 | (0.085 ± 0.038) × 103 | (0.013 ± 0.017) × 103 (undetected in 2 of 4 mice) |
| Eosinophils | (0.2 ± 0.0) × 103 | (0.02 ± 0.02) × 103 (undetected in 2 or 4 mice) | (0.0 ± 0.0) × 103 (undetected in 4 of 4 mice) |
| Monocytes | (0.13 ± 0.05) × 103 | (0.007 ± 0.006) × 103 | (0.002 ± 0.001) × 103 |