TABLE 1.
SAA levels after vaccinationa
| Time after vaccination (h) | Mean SAA (μg/ml) ± SEM in calves vaccinated:
|
|
|---|---|---|
| i.m. | i.n. | |
| First vaccination | ||
| 0 | 51.7 ± 47.0 | 52.9 ± 67.1 |
| 3 | 71.1 ± 86.8 | 46.2 ± 58.4 |
| 8 | 144.0 ± 128.0 | 31.4 ± 24.9 |
| 24 | 392.5 ± 220.2 | 25.6 ± 16.8 |
| 48 | 189.3 ± 225.8 | 26.3 ± 15.0 |
| 144 | 43.5 ± 36.5 | 66.0 ± 91.5 |
| Second vaccination | ||
| 0 | 39.3 ± 25.3 | 21.3 ± 15.9 |
| 24 | 660.0 ± 65.5 | 14.4 ± 3.5 |
a
Two groups of four calves each were vaccinated twice, at a 4-week interval, either i.m. or i.n., with the aroA strain. SAA levels were determined in sera collected on the day of first vaccination (day 0), and at intervals thereafter, and on the day of second vaccination (day 30) and 24 h later.