Table 1.
Five autoimmune HIT (aHIT) disorders.
Name of aHIT Disorder | Concept (Definition) |
---|---|
Delayed-onset HIT | Platelet count fall that begins or worsens despite stopping heparin |
Persisting (refractory) HIT | Delayed platelet count recovery despite stopping heparin (>1 week) |
Heparin “flush” HIT | HIT that occurs with exposure only to small amounts of heparin |
Fondaparinux-induced HIT | HIT associated with proximate exposure to fondaparinux |
Unusually severe HIT | Marked thrombocytopenia, multiple-site thromboses, overt DIC, etc. |
Abbreviations: aHIT, autoimmune heparin-induced thrombocytopenia; DIC, disseminated intravascular coagulation; HIT, heparin-induced thrombocytopenia.