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. 2023 Nov 14;13(11):e075232. doi: 10.1136/bmjopen-2023-075232

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© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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HRs of Cox proportional survival curves for survival probability for each sodium value adjusted for age, sex assigned at birth, a history of chronic kidney disease and a history of hypertension. The grey area indicates the normonatremia. Table shows HRs for covariates and sodium as a continuous variable (A). Cox proportional survival curves at the mean of covariates for (B) unadjusted 6-week mortality stratified by normonatremia, hyponatraemia and hypernatraemia, (C) 6-week mortality adjusted for age, sex assigned at birth, a history of chronic kidney disease and a history of hypertension stratified in normonatremia, hyponatraemia and hypernatraemia, (D) unadjusted 6-week mortality stratified by aetiology. **Indicates a p value<0.01. ***Indicates a p value<0.001.