Figure 2.

OR for adverse outcomes (death/palliative discharge (A), intensive care unit admission (B), invasive ventilation (C)) for each SARS-CoV-2 variant compared with patients in that started having symptoms when the initial variants for patients with hyponatraemia, hypernatraemia or normonatremia at admission. ***Indicates a p value<0.001 for the OR as calculated by binary logistic regression. (D) Incidence of hyponatraemia, normonatremia and hypernatraemia for each variant, *Indicates a p value<0.05 as compared with the first quartile for the χ² statistic with Bonferroni post hoc correction.