Figure 3.

Effect of maternal high-fat diet during lactation on long-term spatial memory analysis using the Barnes maze task in 6-month-old male and female offspring. (A,B) Distance moved during the learning phase representing the capacity to find the escape box during the four days of training, respectively, in male and female offspring. (C,D) Percentages of time spent in the target and other quadrants during the probe test, 72 h after the last day of learning, respectively, in male and female offspring. The dotted line corresponds to the theoretical percentage chance of exploring the quadrant. Values are represented as mean ± SEM. ** p < 0.01 vs. WC using two-way ANOVA followed by Tukey’s post hoc test. n = 13 WC females; n = 11 WH females; n = 6 WC males; n = 10 WH males.