Table 1.
Effect of maternal high-fat diet during lactation on physiological and metabolic parameters in male and female offspring.
| Parameters | WC 
|
WH
|
Significance | WC 
|
WH
|
Significance |
|---|---|---|---|---|---|---|
| Body weight at P21 (g) | 8.6 ± 0.3 | 9.7 ± 0.3 | p = 0.010; ** | 8.2 ± 0.2 | 10.0 ± 0.2 | p = 0.001; *** |
| Body weight at the sacrifice—7 months (g) | 34.3 ± 0.7 | 30.4 ± 1.0 | p = 0.006; ** | 24.2 ± 0.7 | 23.4 ± 0.8 | p = 0.765 |
| Glycemia fasting (6 h) —7 months (mg/dL) |
166.7 ± 5.5 | 157.2 ± 6.8 | p = 0.284 | 154.8 ± 4.8 | 151.4 ± 6.2 | p = 0.666 |
|
Insulinemia fasting (6 h)
—7 months (µg/L) |
0.7 ± 0.05 | 0.5 ± 0.07 | p = 0.030; * | 0.3 ± 0.04 | 0.3 ± 0.01 | p = 0.128 |
| Free fatty acid—7 months (mmol/L) | 0.2 ± 0.03 | 0.1 ± 0.04 | p = 0.862 | 0.2 ± 0.02 | 0.2 ± 0.02 | p = 0.594 |
| Triglyceride—7 months (mg/dL) | 53.7 ± 10.5 | 64.0 ± 7.3 | p = 0.431 | 45.9 ± 3.4 | 48.9 ± 2.9 | p = 0.578 |
| Cholesterol—7 months (mg/dL) | 61.7 ± 10.1 | 65.3 ± 7.9 | p = 0.788 | 50.1 ± 3.7 | 47.7 ± 3.5 | p = 0.659 |
| Temperature (°C) | 37.6 ± 0.1 | 37.5 ± 0.1 | p = 0.540 | 37.4 ± 0.1 | 37.3 ± 0.1 | p = 0.693 |
Values are represented as mean ± SEM. * p < 0.05, ** p < 0.01, *** p < 0.001 vs. WC mice and respective sex using Student’s unpaired t-test. Significant differences are indicated in bold. n = 19 WC females; n = 19 WH females; n = 17 WC males; n = 17 WH males.