TABLE 2.
Abscessed tissues in gnotobiotic gp91phox−/−/NOS2−/− mice colonized with C. albicans wild-type (SC5314) or mutant (efg1/efg1 or efg1/efg1 cph1/cph1) strains
| C. albicans strain | Time (days) | No. of mice with abscesses/no. of mice assayeda
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| St | Eso | To | Pal | PP | MLN | Li | Lu | Sp | K | ||
| Germfree | 0 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 | 0/4 |
| SC5314 | 12-15 | 14/14 | 0/14 | 0/14 | 1/14 | 14/14 | 13/14 | 14/14 | 14/14 | 8/14 | 3/14 |
| efg1/efg1 | 9-15 | 2/7 | 2/7 | 1/7 | 0/7 | 6/7 | 7/7 | 6/7 | 5/7 | 5/7 | 2/7 |
| efg1/efg1 cph1/cph1 | 9-15 | 3/8 | 3/8 | 1/8 | 0/8 | 7/8 | 8/8 | 8/8 | 6/8 | 6/8 | 5/8 |
a
St, stomach; Eso, esophagus; To, tongue; Pal, palate; PP, Peyer's patches; MLN, mesenteric lymph node; Li, liver; Lu, lung; Sp, spleen; K, kidney.