TABLE 3.
Effect of genetic immunization against murine cysticercosis caused by T. crassiceps
| Expt | Immunization | No. of mice | Individual parasite loads (No. of cysts) | Avg loada | Load reduction (%)b |
|---|---|---|---|---|---|
| 1 | Naïve | 9 | 52, 57, 75, 77, 80, 89, 98, 107, 109 | 83 ± 7 | |
| Blank vector | 9 | 67, 75, 88, 89, 90, 95, 101, 101, 111 | 91 ± 5 | ||
| synVW2-1 | 9 | 9, 13, 42, 44, 50, 58, 62, 65, 80 | 47 ± 8 | 43c | |
| 2 | Naïve | 8 | 65, 78, 90, 100, 102, 103, 105, 177 | 102 ± 12 | |
| Blank vector | 9 | 45, 53, 60, 83, 89, 98, 107, 114, 116 | 85 ± 9 | ||
| synVW2-1 | 9 | 35, 46, 47, 48, 49, 54, 59, 72, 72 | 54 ± 4 | 48c |
a
The values are means ± standard errors after 25 days of infection.
b
The parasite load in naïve control mice was defined as 100% to calculate the effect of immunization on the parasite loads in other groups of mice.
c
There was a statistically significant difference between naïve control mice and immunized mice (P < 0.05).