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AA-induced aggregation of platelets and bleeding time of PGHS1Neo/Neo, PGHS1-KO, and WT mice. (A) Representative aggregation tracings for each genotype tested at different AA concentrations are depicted. ASA/WT, WT mice received low-dose aspirin in their drinking water (30 mg/l) for 1 week. (B) Tail bleeding times. Bars represent the mean value (n = 11–15). Each symbol represents the bleeding time of an individual mouse.
