. 2023 Oct 24;15(21):5116. doi: 10.3390/cancers15215116

Table 2.

Median number of cell phenotypes by compartment (n = 68).

Phenotype	Total (Range)	Tumor (Range) *	Stroma (Range) *	p *
Total CK⁺	995.08 (42–610.94)	1707.04 (121.45–6107.18)	-	-
Total CD68⁺	62.24 (1.83–451.88)	74.20 (1.24–396.92)	54.75 (0.00–645.24)	0.938
(M1) CD68⁺MRP8-14⁺CD163^negCD206^negArg-1^neg	0.00 (0.00–21.53)	0.00 (0.00–37.22)	0.00 (0.00–16.94)	0.254
(M1) CD68⁺CD86⁺CD163^negCD206^negArg-1^neg	0.00 (0.00–20.04)	0.00 (0.00–20.68)	0.00 (0.00–70.93)	0.765
(M1) CD68⁺CD86⁺MRP8-14⁺CD163^negCD206^negArg-1^neg	0.00 (0.00–0.94)	0.00 (0.00–4.14)	0.00 (0.00–0.00)	0.605
(M2) CD68⁺CD163⁺MRP8-14^negCD86^neg	28.33 (0.00–215.25)	29.09 (0.00–153.37)	18.12 (0.00–354.64)	0.657
(M2) CD68⁺CD206⁺MRP8-14^negCD86^neg	1.98 (0.00–69.97)	1.58 (0.00–46.28)	1.14 (0.00–191.07)	0.615
(M2) CD68⁺CD163⁺CD206⁺MRP8-14^negCD86^neg	1.55 (0.00–68.94)	1.22 (0.00–44.92)	1.08 (0.00–155.97)	0.574
(M2a) CD68⁺CD163⁺Arg-1⁺MRP8-14^negCD86^neg	0.00 (0.00–15.20)	0.00 (0.00–16.94)	0.00 (0.00–12.46)	0.010
(M2a) CD68⁺CD206+Arg-1⁺MRP8-14^negCD86^neg	0.00 (0.00–2.26)	0.00 (0.00–2.65)	0.00 (0.00–1.66)	0.089
(M2a) CD68⁺CD163⁺CD206⁺Arg-1⁺MRP8-14^negCD86^neg	0.00 (0.00–67.92)	0.00 (0.00–44.01)	0.00 (0.00–155.97)	0.278
(M2b) CD68⁺CD86⁺MRP8-14^neg	0.97 (0.00–23.45)	0.48 (0.00–20.68)	0.00 (0.00–82.76)	0.585
(M2c) CD68⁺CD163⁺Arg-1^negMRP8-14^negCD86^neg	27.89 (0.00–214.71)	28.31 (0.00–153.37)	18.12 (0.00–354.64)	0.951
(M2c) CD68⁺CD206⁺Arg-1^negMRP8-14^negCD86^neg	1.77 (0.00–69.26)	1.56 (0.00–45.37)	1.03 (0.00–191.07)	0.626
(M2c) CD68⁺CD163⁺CD206⁺Arg-1^negMRP8-14^negCD86^neg	0.00 (0.00–43.69)	0.00 (0.00–6.28)	0.00 (0.00–151.81)	0.904
CK⁺PD-L1⁺	0.00 (0.00–1.55)	0.00 (0.00–10.05)	-	-
CD68⁺PD-L1⁺	0.00 (0.00–2.48)	0.00 (0.00–0.00)	0.00 (0.00–0.48)	0.608

Note: (M), macrophages; * p, correlation between tumor and stroma compartment using Kruskal–Wallis test.