. 2023 Oct 24;15(21):5116. doi: 10.3390/cancers15215116

Table 3.

Median distances from CK⁺ malignant cells to different macrophage phenotypes (n = 68).

	Median Distances from CK⁺ (µm)
Phenotype	Overall	* Epithelioid	* Non-Epithelioid	* p	^# Asbestos	^# Non-Asbestos	^# p
Total CD68⁺	73.52	85.49	63.20	0.084	104.34	57.81	0.006
(M1) CD68⁺MRP8-14⁺CD163^negCD206^negArg-1^neg	396.76	396.76	--	--	429.37	396.76	0.972
(M1) CD68⁺CD86⁺CD163^negCD206^negArg-1^neg	363.75	380.13	290.52	0.150	353.23	369.01	0.683
(M1) CD68⁺CD86⁺MRP8-14⁺CD163^negCD206^negArg-1^neg	594.17	594.17	--	--	--	594.17	--
(M2) CD68⁺CD163⁺MRP8-14^negCD86^neg	123.72	127.33	91.79	0.304	170.19	92.69	0.070
(M2) CD68⁺CD206⁺MRP8-14^negCD86^neg	279.00	282.21	243.50	0.565	282.21	275.80	0.805
(M2) CD68⁺CD163⁺CD206⁺MRP8-14^negCD86^neg	305.90	309.01	243.50	0.311	297.79	309.01	0.879
(M2a) CD68⁺CD163⁺Arg-1⁺MRP8-14^negCD86^neg	123.72	127.37	91.79	0.304	170.19	92.69	0.061
(M2a) CD68⁺CD206⁺Arg-1⁺MRP8-14^negCD86^neg	509.77	509.77	--	--	427.64	587.42	0.279
(M2a) CD68⁺CD163⁺CD206⁺Arg-1⁺MRP8-14^negCD86^neg	309.01	314.52	243.50	0.345	317.93	306.11	0.808
(M2b) CD68⁺CD86⁺MRP8-14^neg	336.39	378.78	255.33	0.028	332.19	373.46	0.851
(M2c) CD68⁺CD163⁺Arg-1^negMRP8-14^negCD86^neg	123.72	127.37	91.79	0.304	170.19	92.69	0.061
(M2c) CD68⁺CD206⁺Arg-1^negMRP8-14^negCD86^neg	275.80	284.55	243.50	0.593	293.30	240.00	0.481
(M2c) CD68⁺CD163⁺CD206⁺Arg-1^negMRP8-14^negCD86^neg	345.72	345.72	367.92	1.000	317.93	533.08	0.008
CD68⁺PD-L1⁺	582.32	582.32	--	--	--	582.32	--

Note: (M), macrophages; * p, comparison between epithelioid and non-epithelioid types; ^# p, comparison between asbestos and non-asbestos exposure using Kruskal–Wallis test.