Table 2.

Summary of effects of lactic acid versus HCl on lipopolysaccharide-stimulated RAW 264.7 cells

	Lactic acid (pH 7.0)	Lactic acid (pH 6.5)	HCl (pH 7.0)	HCl (pH 6.5)
NO	↓	↓↓	↑	-
iNOS mRNA	↓	↓↓	↑	↑↑
IL-6	↓	↓↓	-	↓
IL-6 mRNA	↓	↓↓	-	↓
IL-10	↓	↓↓	↓	↓↓↓
IL-10 mRNA	↓↓	↓↓	-	-
IL-6 : IL-10 ratio	-	-	-	↑↑
NF-κB	↓	↓↓	↑	↓

IL, interleukin; iNOS, inducible nitric oxide synthase; NO, nitric oxide. Adapted from Kellum and coworkers [19].