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. 2023 Oct 25;24(21):15587. doi: 10.3390/ijms242115587

Figure 2.

Figure 2

Tyrosine metabolism is downregulated in LRRK2-overexpressing DA neurons. (A) Gene expression in the tyrosine metabolism pathway and rank metric scores. Colors of the squares represent the expression level of the gene, with red for high and blue for low expression, respectively. (B) Enrichment plot of GSEA analysis showing the characteristic downregulation of the tyrosine metabolism pathway. (C) The roles of downregulated genes in the tyrosine metabolism pathway. Red arrows denote downregulation in the LRRK2-overexpressing DA neurons.