Table 2.

Immune parameters at onset of infection, early and late septic shock

Parameter	Chronic alcoholic patients	Nonalcoholic patients	P
IL-10 (pg/ml)
Infection	35 (2–37)	41 (12–392)	0.110
Early septic shock	37 (4–371)	66 (2–255)	0.590
Late septic shock	30 (2–118)	35 (0–81)	0.576
Soluble TNF-RI (pg/ml)
Infection	3440 (1280–6680)*	4750 (3540–7880)	0.153
Early septic shock	10,860 (2260–16,670)*	7170 (3280–14,950)	0.622
Late septic shock	9410 (1240–15,940)	7920 (4130–15,000)	0.775
Soluble TNF-RII (pg/ml)
Infection	7280 (3990–8500)	7180 (5930–8890)	0.668
Early septic shock	8070 (3500–8500)	7900 (5100–10,000)	0.895
Late septic shock	7980 (3050–8500)	8120 (5480–10,660)	0.567
TNF-α (pg/ml)
Infection	10 (4–18)	19 (12–93)	0.048
Early septic shock	14 (1–56)	14 (3–29)	0.385
Late septic shock	10 (1–29)	10 (7–16)	0.723

Values are expressed as median (range). IL, interleukin; TNF, tumour necrosis factor; TNF-R, tumour necrosis factor receptor. *Significant changes from infection to early septic shock, and from early septic shock to late septic shock.