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. 2023 Oct 27;24(21):15658. doi: 10.3390/ijms242115658

Figure 8.

Figure 8

ACLY via lipid synthesis coordinates the combined UBE2C and PLK1 inhibition cell cycle arrest response. The black solid arrows depict processes in which a protein or enzyme has been implicated. The black dashed arrows represent transcription facilitation. The red solid inhibitory arrow signifies the inhibitors effect. The red dashed inhibitory arrow indicates transcriptional repression.