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. 2023 Nov 2;24(21):15910. doi: 10.3390/ijms242115910

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Altered gene expression of death receptors and MMP2. (A) Relative gene expression analysis of DR4 (TNFRSF10A), DR5 (TNFRSF10B), and (B) the metastasis factor MMP2 after treatment with DMAS and shikonin for 24 h in MFS cells. Untreated control cells served as reference value (ratio = 1; mean ± SD, n = 6, measured in triplicate). Statistical significances to the untreated controls are defined as follows: * p < 0.05; *** p < 0.001. Statistical significances between the two cell lines MUG-Myx2a and MUG-Myx2b were marked by means of ^# p < 0.05; ^## p < 0.01.