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Effect of compound 10e on voltage-dependent sodium current (INa) activation and inactivation. (A) Current density of Nav1.5 mediated by control (DMSO) and various concentration of compound 10e. (B) Scatter distribution plot of experimental data (C) Voltage-dependent activation (G/Gmax) and (D) inactivation (I/Imax) of the INa in the absence (blue circles) or presence of 1 μM compound 10e (red circles) or presence of 30 μM compound 10e (green circles).
