Table 1.
Features of recent studies of glucose control in intensive care units
| Reference | ||||
| [2] | [4] | [5] | [7] | |
| Design | Prospective, interventional | Retrospective, observational | Retrospective, observational | Retrospective, observational |
| Target glucose levels (mmol/l) | ||||
| Intervention | 4.4–6.1 | <8.0 | 4.4–7.8 | |
| Control | 10.0–11.1 | Not available | 10.0–11.1 | >12.0 |
| Types of admission (n) | ||||
| Surgical | 1548 | 462 | 573 | 160 |
| Medical | 0 | 61 | 1027 | 0 |
| Cardiac surgery (% of total) | 63 | 85 | 0 | 0 |
| Median APACHE II score | 9 | 16 | 16 | Not available |
| ICU mortality (%) | ||||
| Intervention | 4.6 | Not available | 14.8 | 3.3 |
| Control | 8.0 | 20.9 | ||
| Primary end-points | ICU mortality | ICU mortality | ICU mortality | Infection rate, length of hospital stay |
| Secondary end-points | In-hospital mortality, organ dysfunction, tranfusion rate, critical illness polyneuropathy, infection rate | Organ dysfunction, transfusion rate, length of ICU stay, infection rate | ||
APACHE, Acute Physiology and Chronic Health Evaluation; ICU, intensive care unit.