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. 2023 Nov 2;15(21):5263. doi: 10.3390/cancers15215263

Figure 5.

Figure 5

Four RPL/RPS genes (RPL23, RPL35A, RPL6, and RPS18) were inhibited by drug treatment. (A) representation of fold-change difference between drug-treated groups and placebo. (B) The 3D crystal structure of a ribosome generated by the PyMOL software shows specific localization of RPL23, RPL35A, RPL6, and RPS18 (black arrows). The left two panels show direct physical interaction between RPL6 (highlighted in purple) and RPL35A (highlighted in blue) via hydrogen bonding.