Table 3.
Approximate sensitivity and specificity of antineutrophil cytoplasmic antibody in detecting primary vasculitides
| Sensitivity (%) | Specificity (%) | |
| WG | ||
| cANCA | 64 | 95 |
| PR-3 | 66 | 87 |
| PR-3 + ANCA | 55 | 99 |
| MPA | ||
| pANCA | 58 | 81 |
| MPO | 58 | 91 |
| MPO + ANCA | 49 | 99 |
| WG or MPA | ||
| PR-3 + cANCA or MPO + pANCA | 67–73 | 99 |
cANCA, cytoplasmic antineutrophil cytoplasmic antibody; MPA, microscopic polyangiitis; MPO, myeloperoxidase; pANCA, perinuclear antineutrophil cytoplasmic antibody; PR, proteinase; WG, Wegener's granulomatosis. Data from Hagen and coworkers [22].