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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: Brain Behav Immun. 2023 Sep 7;114:349–359. doi: 10.1016/j.bbi.2023.09.001

Table 5.

Generalized linear models with friend relationship status, support, and strain predicting epigenetic aging.

Horvath Hannum PheraoAge GrimAge DunedinPoAm38
Model β b(SE) p β b(SE) p β b(SE) p β b(SE) p β b(SE) p
Friend status (has friends)
Model 1 −0.005 −0.167 (0.409) 0.68 −0.009 −0.270 (0.312) 0.39 −0.013 0.453 (0.562) 0.42 0.056 1.624 (0.344) <0.001* 0.060 0.019 (0.006) 0.005*
Model 2 −0.002 −0.066 (0.408) 0.87 −0.004 −0.110 (0.294) 0.71 −0.008 0.273 (0.594) 0.65 0.028 0.814 (0.312) 0.01 −0.016 −0.005 (0.006) 0.44
Friend support
Model 1 −0.014 −0.180 (0.170) 0.29 0.002 0.030 (0.137) 0.83 −0.006 −0.077 (0.204) 0.71 0.033 0.379 (0.105) <0.001* 0.045 0.005 (0.002) 0.02*
Model 2 −0.013 −0.163 (0.173) 0.35 0.007 0.090 (0.145) 034 0.002 0.024 (0.215) 0.91 0.023 0.264 (0.090) 0.006* −0.030 −0.004 (0.002) 0.09
Friend strain
Model 1 0.002 0.039 (0.306) 0.90 0.009 0.163 (0.229) 0.48 −0.016 0.328 (0.347) 0.35 0.025 0.432 (0.204) 0.04 0.071 0.013 (0.004) 0.003*
Model 2 −0.002 −0.029 (0.301) 0.92 0.002 0.036 (0.214) 0.87 −0.025 −0.511 (0.330) 0.13 −0.005 −0.088 (0.165) 0.60 0.024 0.004 (0.00−1) 0.21

Note, b = unstandardized coefficient. Bold font denotes statistically significant associations. Asterisks indicate statistically significant associations following false discovery rate correction. Model 1 adjusts for chronological age, biological sex, and self-identified race/ethnicity. Model 2 adjusts for Model 1 variables as well as educational attainment, both’ mass index category, smoking status, and alcohol use. The sample size for the friend status models was n = 3,702 (Model l) and n = 3,627 (Model 2), for the friend support models is n = 3,475, and for the friend strain models is n = 3,473.