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. 2004 Nov 29;9(1):R24–R31. doi: 10.1186/cc3012

Table 2.

Model study: protocol A

Parameter Normal pattern Restrictive pattern Obstructive pattern
V' = 1 V' = 0.8 V' = 0.6 V' = 1 V' = 0.8 V' = 0.6 V' = 1 V' = 0.8 V' = 0.6
Large area
 Leakpause (ml) 191 ± 7 196 ± 6 190 ± 4 190 ± 13 190 ± 15 190 ± 6 196 ± 5 185 ± 6 187 ± 6
 Leakconv (ml) 298 ± 6 315 ± 3a 339 ± 4ab 303 ± 6 330 ± 2a 358 ± 2ab 308 ± 7 309 ± 5 320 ± 10ab
Small area
 Leakpause (ml) 146 ± 2 135 ± 5 135 ± 4 147 ± 8 148 ± 12 137 ± 4 146 ± 9 139 ± 6 141 ± 11
 Leakconv (ml) 239 ± 7 228 ± 3 244 ± 4ab 249 ± 10 243 ± 4 269 ± 7ab 243 ± 14 234 ± 4 254 ± 6ab

Results are means ± SD. V', constant inspiratory flow (litre/s); Leakconv, cuff-leak volume measured when the cuff remained deflated during both inspiration and expiration; Leakpause, cuff-leak volume measured when the cuff was deflated at the end of 3 s of inspiratory pause.

aSignificantly different from the corresponding value at V'I = 1 litre/s.

bSignificantly different from the corresponding value at V'I = 0.8 litre/s.