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. 2023 Jul 31;119(14):2441–2457. doi: 10.1093/cvr/cvad124
Drug or drug combination Dose range (mg/kg) and route Purpose Frequency Maximum # doses
Buprenorphine SR 0.5–1 mg/kg, SQ Relieve pain/stress before MI surgery 1 time before the operation 1
Isoflurane 2%, inhale Aesthetical treatment 1 time before the operation 1
Ketamine/xylazine 100 mg/kg for ketamine, 10 mg/kg for xylazine, ip Analgesic treatment 1 time before harvest 1