Table 2.
Clinical outcomes postprocedure, and at follow-up post-Portico valve implantation.
| Variables | Blumenstein et al., 20228 | Corcione et al., 202013 | Perlman et al.4 | Willson et al.14 | Mollmann3 (PorticoTM DS) | Mollmann3 (FlexNavTM DS) | Möllman et al.15 | Raj R Makkar et al. |
|---|---|---|---|---|---|---|---|---|
| Sample size | 344 | 114 | 57 | 10 | 501 | 500 | 222 | 1034 |
| All-cause mortality, n | – | 16 | 9 | – | – | 10 | – | 53 (14·3%) |
| In-hospital mortality, n | 10 | 0 | – | – | 1 | 0 | – | – |
| Cardiovascular Mortalitya, n | – | – | – | – | 15 | 6 | 8 | – |
| 30 Days mortality, n | 13 | – | 2 | 0 | 16 | 10 | 8 | 13 (3·5%) |
| Strokea, n (in hospital/ follow-up) | 13/– | 0/0 | –/4 | 1/– | 13/– | 16/– | 12/– | 6 |
| MIa, n (in hospital/ follow-up) | 6/– | 0/0 | –/1 | 0/– | 2/– | 1/– | 7/– | – |
| Major bleedinga, n (in hospital/ follow-up) | 2/– | 0/0 | –/4 | – | 26/– | 33/– | 25/– | 22 |
| Major vascular complicationsa, n (in hospital/ follow-up) | 9/– | 0/0 | –/5 | 0/– | 32/– | 41/– | 16/– | 36 |
| AKIa, n (in hospital/ follow-up) | 12/– | – | –/1 | 0/– | 7/– | 4/– | 9/– | 4 |
| PPIa, n (in hospital/ follow-up) | 52/– | 13/14 | –/5 | 0/– | 87/– | 84/– | 30/– | – |
| Coronary Obstruction, n | 0 | – | 0 | – | 2 | 3 | 1 | – |
| Major adverse eventa, n (in hospital/ follow-up) | – | 0/16 | – | – | – | – | – | – |
| Device success, n | 318 | 112 | 43 | 10 | 488 | 488 | 216 | – |
| Annular rupture, n | – | – | – | – | 2 | 1 | 0 | – |
| Valve-in-valve procedure, n | – | 2 | – | – | 0 | 0 | 4 | – |
| AVA, cm2 postprocedure | – | 1.8 (2.2) | 1.27±0.31 | 1.3±0.2 | – | – | 1.9±0.5 | 1·85±0·46 |
a
Data arranged in form of postprocedure outcomes/outcomes at follow-up.