Table 5.
Performance of serum biomarkers in predicting high risk groups among the studied patients (n = 60).
| Variable | Cutoff-point | AUC | Sensitivity | Specificity | PVP | PVN | Accuracy |
|---|---|---|---|---|---|---|---|
| Lymphocytes (10³/ul): | ≤1.3 | 0.809 | 70 % | 70 % | 70 % | 70 % | 70 % |
| Albumin (g/dl): | ≤3.6 | 0.831 | 80 % | 63.3 % | 68.5 % | 76 % | 71.7 % |
| NLR | ≥7.01 | 0.722 | 70 % | 73.3 % | 72.4 % | 71 % | 71.7 % |
| PLR | ≥201.6 | 0.853 | 80 % | 73.3 % | 75 % | 78.5 % | 76.7 % |
| BUN (mg/dl): | ≥20.4 | 0.874 | 80 % | 70 % | 72.7 % | 77.8 % | 75 % |
| B/A | ≥5.3 | 0.831 | 83.3 % | 63.3 % | 69.4 % | 79.2 % | 73.3 % |
| CRP(mg/l): | ≥9.0 | 0.943 | 76.7 % | 66.7 % | 69.7 % | 74 % | 71.7 % |
| D-Dimer (ng/ml): | ≥789.5 | 0.953 | 86.7 % | 76.7 % | 78.8 % | 81.4 % | 81.7 % |
| Troponin I (ng/ml): | ≥0.21 | 0.768 | 90 % | 93.3 % | 93.1 % | 90.3 % | 91.7 % |
| BNP (pg/ml): | ≥176 | 0.779 | 93.3 % | 83.3 % | 84.8 % | 92.6 % | 88.3 % |
AUC area under the ROC curve, PVP predictive value positive, PVN predictive value negative.
NLR neutrophil/lymphocyte ratio, PLR platelet/lymphocyte ratio, BUN blood urea nitrogen, B/A BUN/albumin ratio, CRP C-reactive protein, BNP Brain natriuretic peptide.