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. 2023 Nov 15;7(2):e202302247. doi: 10.26508/lsa.202302247

Figure 1. DOCK1 is down-regulated in placental tissues after unexplained recurrent spontaneous abortion (RSA).

Figure 1.

(A) Comparison of relative mRNA expression levels of the DOCK family in villous tissue from patients with RSA (n = 12) and HCs (n = 9). (B) DOCK1 protein content in HCs (n = 6) and RSA (n = 5) determined using Western blotting (Left). Comparison of DOCK1 protein content in HCs and RSA (Right). (C) Representative immunohistochemical staining of DOCK1 in extravillous trophoblasts. Scale bar: 200 μm. (D) Representative immunohistochemical staining of DOCK1 in cytotrophoblasts and syncytiotrophoblasts. Scale bar: 200 μm. (A, B) Data information: in (A, B), analysis of differences was determined with unpaired two-tailed t test. *P < 0.05, **P < 0.01. ns, not significant.