Table 3.
Comparison of prognostic biomarkers between T0 vs. T1, T2, T3 and T4 and percentage of change (% change) between T1, T2, T3 and T4 vs T0.
| Mean ± SD (T0) | Mean ± SD (T1) | Mean ± SD (T2) | Mean ± SD (T3) | Mean ± SD (T4) | % of change T1 vs T0 |
% of change T2 vs T0 |
% of change T3 vs T0 |
% of change T4 vs T0 |
|
|---|---|---|---|---|---|---|---|---|---|
| Glycemia (mg/dL) | 100.52 ± 11.93 | 91.97 ± 11.19*** | 90.45 ± 10.88*** | 95.41 ± 11.25** | 97.6 ± 12.16 | −8.51 % | −10.02 % | −5.08 % | −2.82 % |
| Insulin (microU/mL) | 7.83 ± 4.80 | 6.74 ± 4.40* | 6.16 ± 3.64** | 6.59 ± 3.60* | 6.84 ± 3.75 | −13.95 % | −21.29 % | −15.84 % | −12.59 % |
| HOMA-IR index | 2.04 ± 1.58 | 1.60 ± 1.26** | 1.44 ± 1.47** | 1.61 ± 1.08* | 1.69 ± 1.06 | −21.88 % | −29.60 % | −21.20 % | −17.26 % |
| Triglycerides (mg/dL) | 103.17 ± 44.37 | 94.24 ± 41.35 | 89.86 ± 36.21* | 86.76 ± 42.69* | 94.83 ± 41.96 | −8.66 % | −12.90 % | −15.91 % | −8.08 % |
| HDL (mg/dL) | 62.62 ± 16.09 | 61.00 ± 13.71 | 60.62 ± 13.56 | 65.41 ± 12.82 | 64.38 ± 15.59 | −2.59 % | −3.19 % | 4.46 % | 2.81 % |
| LDL (mg/dL) | 136.00 ± 28.93 | 125.07 ± 28.22** | 129.14 ± 27.33 | 129.55 ± 24.20 | 127.76 ± 23.65* | −8.04 % | −5.04 % | −4.74 % | −6.06 % |
| Total cholesterol (mg/dL) | 216.45 ± 39.28 | 207.38 ± 37.43* | 208.41 ± 37.20 | 206.59 ± 32.01* | 214.83 ± 33.52 | −4.19 % | −3.71 % | −4.56 % | −0.75 % |
| Progesterone (ng/mL) | 0.49 ± 0.40 | 0.45 ± 0.19 | 1.16 ± 3.53 | 1.01 ± 3.31 | 0.71 ± 1.36 | −6.12 % | 138.78 % | 106.12 % | 44.90 % |
| Testosterone (ng/mL) | 0.31 ± 0.26 | 0.20 ± 0.17** | 0.24 ± 0.16** | 0.27 ± 0.17 | 0.27 ± 0.17 | −35.39 % | −23.55 % | −12.72 % | −14.77 % |
| hs-Troponin (ng/L) | 2.97 ± 1.21 | 2.86 ± 2.80 | 2.93 ± 1.16 | 3.14 ± 1.95 | 2.66 ± 1.51 | −3.70 % | −1.35 % | 5.72 % | −10.44 % |
Abbreviations: HDL, high-density lipoprotein; LDL, low-density lipoprotein; hs, high sensitive; T0, baseline; after 3 (T1); 6 (T2); 12 (T3), and 24 (T4) months after the lifestyle intervention; bold values denote statistical significance with a p < 0.05 (*); p < 0.01 (**); or p < 0.001 (***).