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. 2023 Mar 16;45(4):2511–2523. doi: 10.1007/s11357-023-00771-z

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© The Author(s), under exclusive licence to American Aging Association 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 1 — Manhattan plot of the frailty GWAS in the UK Biobank. Manhattan plot for the discovery GWAS of frailty (n = 386,565). Green dots indicate independent significant leading SNPs that have been reported to be associated with traits other than frailty; Red dots indicate independent significant leading SNPs that have never been reported before