Table 2.

Physiological parameters for IP${}_3$ production and degradation, ATP degration and NADH production rate [23, 40, 56, 57]

Symbol	Parameter	Value
$V_{\mathit{PLC}}$	Maximal-rate of PLC	$0.3\mu M{s}^{-1}$
$K_{\mathit{PLC}}$	Half-activation constant of PLC	$0.2\mu M$
$k_{\mathit{deg}}$	IP3 degradation rate constant via phosphorylation	$0.5s^{-1}$
$K_{\mathit{deg}}$	Half-activation constant of IP3 kinases	$0.1\mu M$
$V_{\mathit{AGC}}$	Rate constant of NADH production	$25\mu M{s}^{-1}$
$K_{\mathit{AGC}}$	Dissociation constant of $C{a}^{2+}$ from AGC	$0.14\mu M$
$C_m$	Mitochondrial calcium concentration	$1.3\mu M$
$V_M$	Mitochondrial membrane potential	160mV
$AT{P}_c$	Cytosolic ATP concentration	$0.1\mu M$