Table 2.
Subgroup analysis according to LF/HF ratio: Hemodynamic data
| In all subject | Low ratio (n = 45) |
High ratio (n = 14) |
P value | Group | Time | Time*Group |
|---|---|---|---|---|---|---|
| HR, bpm | 0.409 | 0.000 | 0.584 | |||
| T0 | 68 [60–76] | 77 [66–82] | 0.203 | |||
| T1 | 72 [61–79] | 70 [63–80] | 0.843 | |||
| T2 | 58 [53–67] | 60 [54–68] | 0.675 | |||
| T3 | 61 [56–68] | 63 [60–65] | 0.346 | |||
| SBP, mmHg | 0.652 | 0.000 | 0.575 | |||
| T0 | 152 [134–168] | 145 [140–157] | 0.399 | |||
| T1 | 135 [126–149] | 141 [118–163] | 0.569 | |||
| T2 | 130 [111–156] | 132 [106–153] | 0.741 | |||
| T3 | 121 [109–142] | 124 [103–137] | 0.569 | |||
| MBP, mmHg | 0.221 | 0.000 | 0.080 | |||
| T0 | 106 [98–121] | 99 [92–113] | 0.069 | |||
| T1 | 94 [84–105] | 95 [84–110] | 0.606 | |||
| T2 | 94 [80–111] | 88 [80–105] | 0.351 | |||
| T3 | 89 [81–104] | 84 [74–94] | 0.179 | |||
| DBP, mmHg | 0.498 | 0.000 | 0.824 | |||
| T0 | 82 [76–89] | 76 [71–89] | 0.197 | |||
| T1 | 72 [63–79] | 70 [62–83] | 0.933 | |||
| T2 | 72 [61–83] | 66 [59–84] | 0.445 | |||
| T3 | 70 [61–80] | 65 [58–76] | 0.404 | |||
| In D group |
Low ratio (n = 24) |
High ratio (n = 6) |
P value | Group | Time | Time*Group |
| HR, bpm | 0.614 | 0.000 | 0.626 | |||
| T0 | 71 [61–77] | 68 [61–82] | 0.965 | |||
| T1 | 74 [65–80] | 68 [63–80] | 0.571 | |||
| T2 | 55 [51–62] | 54 [46–60] | 0.948 | |||
| T3 | 59 [54–67] | 62 [59–65] | 0.405 | |||
| SBP, mmHg | 0.757 | 0.000 | 0.671 | |||
| T0 | 155 [130–169] | 152 [140–173] | 0.742 | |||
| T1 | 135 [129–152] | 149 [118–166] | 0.424 | |||
| T2 | 152 [134–168] | 143 [132–167] | 0.954 | |||
| T3 | 139 [124–148] | 135 [130–151] | 0.756 | |||
| MBP, mmHg | 0.666 | 0.000 | 0.194 | |||
| T0 | 112 [97–121] | 108 [93–119] | 0.879 | |||
| T1 | 95 [88–105] | 93 [83–118] | 0.729 | |||
| T2 | 110 [95–116] | 101 [88–116] | 0.579 | |||
| T3 | 100 [89–108] | 92 [88–114] | 0.669 | |||
| DBP, mmHg | 0.552 | 0.000 | 0.110 | |||
| T0 | 83 [77–88] | 85 [68–103] | 0.577 | |||
| T1 | 70 [64–79] | 67 [61–84] | 0.835 | |||
| T2 | 80 [71–91] | 74 [61–87] | 0.424 | |||
| T3 | 77 [67–84] | 66 [60–88] | 0.304 | |||
| In P group |
Low ratio (n = 21) |
High ratio (n = 8) |
P value | Group | Time | Time*Group |
| HR, bpm | 0.202 | 0.016 | 0.329 | |||
| T0 | 64 [58–75] | 78 [70–83] | 0.052 | |||
| T1 | 66 [59–78] | 72 [60–84] | 0.657 | |||
| T2 | 63 [56–71] | 64 [59–79] | 0.790 | |||
| T3 | 63 [59–68] | 64 [60–72] | 0.795 | |||
| SBP, mmHg | 0.663 | 0.000 | 0.361 | |||
| T0 | 149 [136–168] | 141 [130–148] | 0.124 | |||
| T1 | 135 [120–146] | 138 [103–163] | 0.731 | |||
| T2 | 112 [102–124] | 110 [101–143] | 0.728 | |||
| T3 | 109 [103–121] | 105 [97–122] | 0.463 | |||
| MBP, mmHg | 0.294 | 0.000 | 0.076 | |||
| T0 | 104 [97–124] | 99 [91–101] | 0.048 | |||
| T1 | 93 [81–105] | 98 [74–108] | 0.607 | |||
| T2 | 78 [73–91] | 81 [71–87] | 0.933 | |||
| T3 | 80 [73–92] | 77 [68–82] | 0.272 | |||
| DBP, mmHg | 0.940 | 0.000 | 0.456 | |||
| T0 | 81 [75–90] | 73 [71–78] | 0.042 | |||
| T1 | 75[61–79] | 73 [61–82] | 0.952 | |||
| T2 | 60 [56–71] | 64 [51–74] | 0.876 | |||
| T3 | 62 [53–76] | 62 [56–71] | 1.000 |
Values are median [interquartile range]
Low ratio, LF/HF ratio ≤ 2.3; high ratio, LF/HF ratio > 2.3
D group, dexmedetomidine group; P group, propofol group
HR, heart rate; SBP, systolic blood pressure; MBP, mean blood pressure; DBP, diastolic blood pressure
T0, baseline; T1, 10 min after spinal anesthesia; T2, 10 min after sedation; T3, 20 min after sedation