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(A) rep is sufficient to confer the 2A7 phenotype. S. lividans TK24 transformed with pOSI700 (top) or pOSI.rep (bottom) was inoculated onto R5 or SMM glucose (Glu) agar and grown at 30°C for 6 or 3 days, respectively. (B) rep increases antibiotic production in S. coelicolor M145. S. coelicolor M145 containing the control vector pMBD14 (top) or pMBD.rep (bottom) was inoculated onto R5 or SMM glucose agar and grown for 4 or 5 days, respectively.
