Table 2.

Cardiac function assessed by echocardiography with/without losartan.

	Control	BO	losartan	BO + losartan
n	6	7	6	5
EF	67 ± 2.0	60 ± 4.4**	66 ± 1.4	67 ± 1.3##
LVEDV	0.23 ± 0.01	0.21 ± 0.02	0.22 ± 0.01	0.20 ± 0.01
LVESV	0.074 ± 0.01	0.085 ± 0.02	0.077 ± 0.006	0.066 ± 0.003#
%FS	32 ± 1.4	28 ± 2.8**	31 ± 0.9	32 ± 0.9##
LVIDd	4.5 ± 0.09	4.4 ± 0.16	4.5 ± 0.07	4.3 ± 0.07
LVIDs	3.1 ± 0.1	3.2 ± 0.2	3.1 ± 0.09	3.0 ± 0.04##
HR	428 ± 37	402 ± 28	434 ± 16	412 ± 62
SV	0.15 ± 0.01	0.13 ± 0.01**	0.15 ± 0.01	0.13 ± 0.01
CO	59 ± 5.6	46 ± 4.8**	57 ± 2.1	51 ± 5.0
IVSTd	0.49 ± 0.04	0.50 ± 0.03	0.52 ± 0.04	0.50 ± 0.05
IVSTs	0.88 ± 0.05	0.83 ± 0.03	0.89 ± 0.04	0.90 ± 0.05
LVPWTd	0.50 ± 0.03	0.49 ± 0.04	0.50 ± 0.04	0.52 ± 0.02
LVPWTs	0.98 ± 0.02	0.83 ± 0.06**	0.95 ± 0.04	0.91 ± 0.05#

EF (%), ejection fraction; LVEDV (mL), left ventricular end-diastolic volume; LVESV (mL), left ventricular end-systolic volume; FS (%), fractional shortening; LVIDd (mm), left ventricular internal dimension at end-diastole; LVIDs (mm), left ventricular internal dimension at end-systole; HR (bpm), heart rate; SV (mL), stroke volume; CO (mL/min), cardiac output; IVSTs (mm), interventricular septum thickness at end-systole; IVSTd (mm), interventricular septum thickness at end-diastole; LVPWTd (mm), posterior wall thickness at end-diastole; LVPWTs (mm), posterior wall thickness at end-systole.

*P < 0.05, **P < 0.01 vs. Control.

^#P < 0.05, ^##P < 0.01 vs. BO.