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. 2023 Nov 15;14:7384. doi: 10.1038/s41467-023-42390-4

Fig. 8. SMN-deficient cells are sensitive to DNA damage.

Fig. 8

a Survival curve was determined by the colony-forming ability to UV-C of cells expressing (+Dox) or not (−Dox) Sh6-SMN. Counting of clones was normalized to non-irradiated condition. b, c Clonogenic assay of cells cultured with different quantities of oxygen (3% or 20%) in the presence (ShSCRB = ShSCRAMBLE) or absence of SMN (Sh5-SMN and Sh6-SMN). Counting of clones was normalized (a) to 20% oxygen or (b) to ShSCRB. Data are represented as mean values of the triplicate +/− SEM. Source data of graphs are provided as a Source Data file.