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. 2023 Oct 27;150(21):dev201593. doi: 10.1242/dev.201593

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© 2023. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 8. — Proteomic analysis of Actl7b-deficient testis. (A-C) Volcano plots showing differential abundance (DA) of proteins in Actl7b^+/− compared with Actl7b^+/+ (A), in Actl7b^−/− compared with Actl7b^+/− (B) and in Actl7b^−/− compared with Actl7b^+/+ (C) testis. Proteins showing a significant DA are indicated in teal (less abundant) and yellow (more abundant) (adjusted P-value>0.05). Top DA proteins are labeled with their corresponding gene symbol. (D,E) Venn diagrams showing the overlap of significantly higher (D) and lower (E) abundance proteins in the comparisons of Actl7b^−/− with Actl7b^+/+, and Actl7b^−/− with Actl7b^+/+ testis (adjusted P-value≤0.05, LFC≤1).