FIG. 9.

Protection of mice from the lethality of TSST-1 by anisodamine. Injection of TSST-1 and treatment of d-galactosamine-sensitized mice with anisodamine (50 mg/kg) were carried out as described in the legend to Fig. 8. d-Galactosamine-sensitized mice injected only with saline (with no TSST-1) were used as controls (open squares). Treatment with anisodamine of mice injected with TSST-1 was as follows: open circles, none; open triangles, 10 mg/kg of body weight; closed triangles, 50 mg/kg of body weight. *, P < 0.05 compared with the TSST-1-injected, untreated mice (open circles).