TABLE 2.
IgG and IgA antibody levels measured using recombinant staphylococcal proteinsa
| Protein | IgG for:
|
IgA for:
|
||||||
|---|---|---|---|---|---|---|---|---|
| Infected patients (n = 42) | Healthy
|
Patient (n = 33) | Healthy
|
|||||
| Total (n = 40) | Noncarrier (n = 9) | Carrier (n = 15) | Total (n = 40) | Noncarrier (n = 9) | Carrier (n = 15) | |||
| SdrC | 416 (31-1,877) | 276 (92-1,796) | 278 (67-568) | 308 (9-1,796) | 433 (42-1,125) | 398 (0-1,182) | 545 (24-1,017) | 396 (35-893) |
| SdrD | 397 (48-1,119) | 98 (50-1,352) | 110 (5-195) | 127 (28-717) | 462 (66-1,472) | 428 (0-1,063) | 423 (65-998) | 433 (34-898) |
| SdrE | 378 (34-1,545) | 329 (164-2,740) | 336 (135-653) | 322 (86-2,740) | ND | ND | ND | ND |
| ClfA | 135 (38-1,032) | 141 (97-685) | 147 (56-517) | 138 (42-422) | 25 (6-108) | 34 (0-333) | 34 (0-110) | 24 (1-333) |
| ClfB | 216 (65-1,043) | 385 (186-1,359) | 466 (135-980) | 264 (115-629) | 52 (10-260) | 41 (0-235) | 34 (20-85) | 44 (12-186) |
| IsdB | 909 (105-3,351) | 979 (768-2,713) | 971 (621-1,522) | 1011 (31-2,552) | 113 (35-273) | 87 (0-319) | 120 (63-228) | 72 (0-319) |
| HarA | 462 (74-1,546) | 276 (180-815) | 414 (123-566) | 194 (0-705) | 265 (26-1,127) | 88 (19-517) | 71 (27-182) | 87 (19-517) |
| StbA | 854 (170-3,505) | 734 (409-2,809) | 888 (306-1,563) | 890 (301-1,999) | 45 (5-225) | 28 (1-245) | 31 (14-133) | 30 (4-245) |
| Mrp | 176 (45-789) | 126 (65-1,656) | 123 (26-243) | 123 (15-1,489) | 14 (2-139) | 9 (0-116) | 13 (5-31) | 10 (0-30) |
| FnbpA | 234 (0-2,364) | 183 (138-983) | 206 (73-311) | 181 (55-399) | ND | ND | ND | ND |
| Pbp2a | 118 (17-536) | 73 (49-828) | 90 (35-135) | 81 (16-682) | 37 (0-399) | 30 (0-234) | 22 (5-92) | 29 (0-105) |
| Map-w | 311 (59-2,923) | 332 (169-1,086) | 516 (115-1,086) | 270 (56-979) | 138 (28-427) | 103 (1-626) | 194 (4-365) | 75 (16-397) |
| Enolase | 96 (34-378) | 54 (38-163) | 79 (36-148) | 42 (26-67) | ND | ND | ND | ND |
| EbpS | 341 (84-1,737) | 228 (158-812) | 250 (104-737) | 225 (69-529) | 34 (8-299) | 19 (0-225) | 24 (1-50) | 18 (4-225) |
| SA2505 | 88 (7-993) | 100 (61-322) | 118 (37-225) | 108 (19-322) | 26 (0-727) | 23 (0-420) | 25 (0-420) | 23 (2-345) |
| SA0688 | 217 (0-1,267) | 90 (68-807) | 93 (41-807) | 88 (45-193) | 6 (2-329) | 9 (1-32) | 10 (2-23) | 9 (2-32) |
| SA0799 | UD | UD | UD | UD | UD | UD | UD | UD |
| Coa | 16 (5-84) | 34 (23-204) | 36 (12-187) | 35 (14-204) | 22 (0-90) | 36 (0-223) | 48 (3-155) | 49 (3-110) |
| Fib | 74 (8-597) | 152 (110-775) | 142 (72-296) | 131 (52-563) | 24 (0-128) | 32 (0-116) | 40 (6-116) | 29 (4-102) |
a
Median ELISA units reflecting antibody levels are shown for each recombinant protein in each donor group. Significantly increased values for infected patient versus healthy patient or noncarrier versus carrier comparisons are shown in boldface characters. Minimum and maximum ELISA units are shown in parentheses. Noncarriers and carriers tested negative and positive, respectively, at least twice. ND, not determined; UD, underdetection.