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. 2023 Nov 7;35:100778. doi: 10.1016/j.lanepe.2023.100778

Table 1.

Prevalent patients with S/V prescriptions.

Drug(s) 2016
2017
2018
2019
Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4
S/V total (% of S/V total) 5260 (100%) 14,521 (100%) 21,181 (100%) 27,142 (100%) 33,722 (100%) 40,489 (100%) 47,034 (100%) 54,703 (100%) 63,632 (100%) 72,704 (100%) 81,644 (100%) 92,798 (100%) 107,069 (100%) 121,044 (100%) 134,080 (100%) 149,169 (100%)
S/V alone (% of S/V total) 5231 (99.4%) 14,366 (98.9%) 20,905 (98.7%) 26,747 (98.5%) 33,164 (98.3%) 39,621 (97.9%) 45,811 (97.4%) 53,148 (97.2%) 61,586 (96.8%) 70,129 (96.5%) 78,501 (96.2%) 88,926 (95.8%) 102,343 (95.6%) 115,240 (95.2%) 127,190 (94.9%) 140,347 (94.1%)
S/V + SGLT2i (% of S/V total) 29 (0.6%) 156 (1.1%) 276 (1.3%) 395 (1.5%) 558 (1.7%) 868 (2.1%) 1223 (2.6%) 1556 (2.8%) 2047 (3.2%) 2576 (3.5%) 3143 (3.8%) 3872 (4.2%) 4726 (4.4%) 5804 (4.8%) 6890 (5.1%) 8822 (5.9%)
Drug(s) 2020
2021
2022
2023
Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2
S/V total (% of S/V total) 165,676 (100%) 174,480 (100%) 184,947 (100%) 195,261 (100%) 207,290 (100%) 219,762 (100%) 235,367 (100%) 252,061 (100%) 270,326 (100%) 286,160 (100%) 301,287 (100%) 318,595 (100%) 337,463 (100%) 351,262 (100%)
S/V alone (% of S/V total) 154,620 (93.3%) 161,763 (92.7%) 170,448 (92.2%) 177,760 (91.0%) 184,194 (88.9%) 188,633 (85.8%) 192,310 (81.7%) 186,971 (74.2%) 182,817 (67.6%) 175,685 (61.4%) 170,785 (56.7%) 166,561 (52.3%) 163,538 (48.5%) 158,833 (45.2%)
S/V + SGLT2i (% of S/V total) 11,056 (6.7%) 12,717 (7.3%) 14,500 (7.8%) 17,501 (9.0%) 23,096 (11.1%) 31,128 (14.2%) 43,057 (18.3%) 65,090 (25.8%) 87,509 (32.4%) 110,476 (38.6%) 130,502 (43.3%) 152,035 (47.7%) 173,925 (51.5%) 192,429 (54.8%)

S/V = sacubitril/valsartan, SGLT2i = sodium–glucose co-transporter 2 inhibitor.