TABLE 4.

Surface proteins in S. aureus and S. epidermidis

Locus	Functiona	Functional name	Gene(s)	SDb present	LPXTGc	YSIRKd present
S. aureus surface proteinse
SA0856	a	Clumping factor A	clfA	+	LPDTG	+
SA2652	a	Clumping factor B	clfB	+	LPETG	+
SA2511	a	Fibronectin binding protein A	fnbA		LPETG	+
SA2509	a	Fibronectin binding protein B	fnbB		LPETG	+
MW2612g	a	Collagen adhesion	cna		LPKTG
SA0608	a	SdrC	sdrC	+	LPETG	+
SA0609	a	SdrD	sdrD	+	LPETG	+
SA0610	a	SdrE	sdrE	+	LPETG	+
SA0095	a,b	Protein A	spa		LPETG	+
SA0050	e	Methicillin resistance surface protein	pls	+	LPDTG	+
SA2676	e	Cell wall surface anchor protein	sasA		LPDTG
SA2150	e	Phosphoglucomutase (FmtB/Mrp)	sasB		LPDTG	+
SA1806	e	Cell wall surface anchor protein	sasC		LPNTG	+
SA0119	e	Cell wall surface anchor protein	sasD		LPAAG
SA1140	d	Cell wall surface anchor protein	sasE (isdA)		LPKTG	+
SA2668	e	Cell wall surface anchor protein	sasF		LPKAG
SA2505	e	Cell wall surface anchor protein	sasG (aap)		LPKTG	+
SA0024	e	5′ nucleotidase family protein	sasH		LPKTG
SA1781	g	Cell wall surface anchor protein	sasI (harA)		LPKTG	+
SA1138	d	Cell wall surface anchor protein	sasJ (isdB)		LPKTG	+
SA2381h	d	Cell wall surface anchor protein	sasK		LPKTG
SA1141	e	Cell wall surface anchor protein (NPQTN)	isdC		NPQTN
SA2002	a	Extracellular adherence protein	eap, map
SA0858	a	Extracellular matrix and plasma binding protein	empbp
SA1472	a	Cell wall-associated fibronectin binding protein	ebh			+
SA1164	a	Fibrinogen binding-related protein	fib
SA1168	a	Fibrinogen binding protein	efb
SA1522	a	Elastin binding protein	ebp
SA1062	a	Biofunctional autolysin	atl
S. epidermidis surface proteinsf
SE0026	a	SdrF (truncated) (not all strains have SdrF)	sdrF			+
SE0207	a	SdrG	sdrG	+	LPDTG
SE1487	a	SdrH	sdrH	+
SE1316	e	Cell wall surface anchor protein	sesA		LPLAG	+
SE2162	e	Cell wall surface anchor protein	sesB		LPNTG
SE2264	e	Cell wall surface anchor protein	sesC		LPATG
SE2392i	c	Cell wall surface anchor protein	sesD (bhp)		LPQTG	+
SE0719	e	Cell wall surface anchor protein	sesE		LPETG	+
SE2398	e	Cell wall surface anchor protein	sesF (aap)		LPDTG	+
SE1482i	e	Cell wall surface anchor protein	sesG		LPDTG	+
SE1483	e	Cell wall surface anchor protein	sesH		LPETG
SE1654i	e	Cell wall surface anchor protein	sesI		LPETG
SE1500j	e	Cell wall surface anchor protein	sesJ		LPKTG
SE1501j	e	Cell wall surface anchor protein	sesK		LPNTG
SE1011	a	Cell wall associated fibronectin binding protein	ebh			+
SE1048	a	Elastin binding protein	ebp
SE0636	a,f	Bifunctional autolysin	altE
SE0775	a	Fibrinogen binding protein	fbe

^aa, adherence to host tissue (extracellular matrix, fibrinogen, fibronectin, collagen, elastin, endothelial and epithelial cells); b, evasion of host defense; c, biofilm formation; d, binding to heme-iron; e, unknown; f, adherence to synthetic material (implanted medical devices); g, haptoglobin receptor A.

^bSD, Serine-aspartate dipeptide repeats found in staphylococcal cell wall-attached proteins.

^cLPXTG, attachment sequence for gram-positive cell wall-attached proteins.

^dYSIRK, signal peptide YSIRK for gram-positive cell wall-attached proteins.

^eS. aureus COL loci unless indicated otherwise.

^fS. epidermidis RP62a loci unless indicated otherwise.

^gS. aureus MW2.

^hS. aureus N315.

ⁱOnly in S. epidermidis RP62a.

^jOnly in S. epidermidis ATCC 12228.