Table 1. Cohort Demographics.
| Characteristic, No. | Cohort | Total | ||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RAPBI | Pilot-RAPBI | NCH | KKI | LLU | DU 1 | DU 2 | BCM 1a | BCM 2a | BCM 3a | MCRI | UT Houstonb | |||||||||||||
| Participants | ||||||||||||||||||||||||
| Total | 109 | 22 | 53 | 42 | 52 | 44 | 49 | 99 | 32 | 31 | 22 | 43 | 598 | |||||||||||
| msTBI group | 53 | 13 | 29 | 29 | 21 | 18 | 22 | 50 | 15 | 22 | 22 | 20 | 314 | |||||||||||
| Comparison group | 56 | 9 | 24 | 13 | 31 | 26 | 27 | 49 | 17 | 9 | 0 | 23 | 284 | |||||||||||
| Sex | ||||||||||||||||||||||||
| Male | 72 | 14 | 37 | 27 | 34 | 20 | 23 | 71 | 21 | 21 | 17 | 29 | 386 | |||||||||||
| Female | 37 | 8 | 16 | 15 | 18 | 24 | 26 | 28 | 11 | 10 | 5 | 14 | 212 | |||||||||||
| Age, y | ||||||||||||||||||||||||
| Mean (SD) | 15.61 (2.79) | 16.14 (1.86) | 11.80 (2.38) | 14.57 (2.43) | 12.89 (3.45) | 14.34 (2.80) | 14.60 (2.73) | 13.53 (2.83) | 14.56 (2.62) | 15.48 (2.34) | 11.13 (2.86) | 12.70 (2.41) | 14.05 (3.06) | |||||||||||
| Range | 8.40 to 19.70 | 12.10 to 18.57 | 8.16 to 16.52 | 8.12 to 18.98 | 5.45 to 17.78 | 8.52 to 19.00 | 8.52 to 18.97 | 7.44 to 18.70 | 10.67 to 19.40 | 10.61 to 18.51 | 5.83 to 16.83 | 8.16 to 16.91 | 5.45 to 19.70 | |||||||||||
| TSI range, wkc | ||||||||||||||||||||||||
| Period 1 | 3.9-36.3 | 11.7-36.2 | 58.7-42.4 | 4.1-14.6 | 1.0-2.6 | 15.6-56.2 | NA | 11.7-28.8 | 0.14-15.4 | 2.4-60.0 | 4.5-37.6 | 4.1-18.3 | NA | |||||||||||
| Period 2 | 49.2-82.7 | 59.1-68.6 | NA | 51.9-76.0 | 48.1-62.1 | NA | NA | 49.6-117.8 | NA | NA | 99.8-124.0 | 55.8-63.0 | NA | |||||||||||
| Scans | ||||||||||||||||||||||||
| Total | 158 | 24 | 53 | 55 | 100 | 44 | 49 | 134 | 32 | 31 | 43 | 60 | 783 | |||||||||||
| Longitudinal | 49 | 2 | NA | 13 | 48 | NA | NA | 35 | NA | NA | 21 | 17 | 185 | |||||||||||
Abbreviations: BCM, Baylor College of Medicine; DU; Deakin University; KKI, Kennedy-Krieger Institute; LLU, Loma Linda University; MCRI, Murdoch Children’s Research Institute; msTBI, mild complicated-severe traumatic brain injury; NA, not applicable; NCH, Nationwide Children’s Hospital; RAPBI, Recovery After Pediatric Injury; TSI, time since injury; UT, University of Texas.
a
Indicates sites with comparison groups consisting of individuals with orthopedic injury.
b
UT Houston had both orthopedic individuals and healthy controls in the comparison group.
c
Studies with 2 time periods are longitudinal studies.