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. 2023 Nov 15;6(11):e2343410. doi: 10.1001/jamanetworkopen.2023.43410

Table 3. BRIEF Score Associations.

Region and subregion BRIEF Behavioral Regulation Index BRIEF Metacognition Index BRIEF Global Executive Composite
P valuea Adjusted P value β-Value (95% CI) P valuea Adjusted P value β-Value (95% CI) P valuea Adjusted P value β-Value (95% CI)
Total volume .005 .06 −152.9 (−253.7 to −52.0) .002 .02 −202.5 (−319.5 to −85.5) <.001 .008 −208.9 (−319.4to −98.5)
Corpus medullare .31 .98 −11 (−32.0 to 10.1) .08 .60 −23.4 (−49.1 to 2.4) .08 .60 −22.1 (−46.5 to 2.3)
Anterior lobe
Lobule I-III .23 .94 −1.5 (−3.8 to 0.9) .02 .20 −3.0 (−5.4 to −0.6) .08 .60 −2.2 (−4.6 to 0.2)
Lobule IV .05 .41 −5.6 (−11.0 to −0.2) .005 .05 −8.7 (−14.4 to −3.0) .007 .07 −8.2 (−13.8 to −2.6)
Lobule V .03 .27 −6.1 (−11.4 to −0.8) .02 .16 −7.1 (−12.7 to −1.6) .02 .16 −7.1 (−12.5 to −1.6)
Posterior lobe
Lobule VI .34 .99 −5.9 (−18.2 to 6.3) .06 .48 −13.7 (−27.2 to −0.2) .16 .85 −9.6 (−23.0 to 3.7)
Crus I .02 .22 −27.9 (−50.2 to −5.6) .09 .66 −21.1 (−45.0 to 2.7) .03 .26 −28.0 (−51.2 to −4.8)
Crus II .54 >.99 −4.5 (−19.0 to 10.0) .08 .58 −14.7 (−30.4 to 1.1) .19 .90 −10.7 (−26.6 to 5.2)
Lobule VII B .76 >.99 2.0 (−10.5 to 14.4) .12 .76 −10.7 (−24.0 to 2.5) .19 .90 −9.0 (−22.5 to 4.4)
Lobule VIIIA .31 .98 −6.4 (−18.7 to 6.0) .81 >.99 1.6 (-11.4 to 14.6) .95 >.99 −0.4 (−13.4 to 12.6)
Lobule VIIIB .62 >.99 −1.6 (−7.9 to 4.7) .58 >.99 −2.1 (−9.6 to 5.4) .41 >.99 −3.0 (−10.3 to 4.2)
Lobule IX .13 .78 −4.3 (−9.9 to 1.2) .16 .85 −5.0 (−11.8 to 1.8) .32 .99 −3.4 (−10.0 to 3.3)
Flocculonodular lobe, lobule X .19 .90 0.7 (−0.3 to 1.7) .32 >.99 0.6 (−0.5 to 1.7) .53 >.99 0.3 (−0.7 to 1.4)
Vermis
VI .12 .76 1.7 (−1.3 to 4.7) .96 >.99 0.5 (−2.6 to 3.7) .85 >.99 1.1 (−2.0 to 4.2)
VII .86 >.99 −1.5 (−3.3 to 0.3) .81 >.99 0.0 (−2.1 to 2.0) .50 >.99 −0.2 (−2.2 to 1.8)
VIII .78 >.99 0.3 (−3.0 to 3.6) .86 >.99 0.4 (−3.2to 4.1) .73 >.99 1.2 (−2.3 to 4.7)
IX .37 .99 −0.2 (−1.8 to 1.4) .95 >.99 0.2 (−1.6 to 1.9) .84 >.99 0.3 (−1.4 to 2.0)
X .27 .97 0.3 (−0.3 to 0.9) .75 >.99 0.0 (−0.7 to 0.7) .47 >.99 0.1 (−0.6 to 0.7)

Abbreviations: BRIEF, Behavior Rating Inventory of Executive Functioning.

a

The threshold for significance for the raw P values is P < .0045.