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. 2023 Oct 16;15(10):e47151. doi: 10.7759/cureus.47151

Table 5. Univariate and multivariate predictors of mortality on stepwise logistic regression analysis.

HE, hepatic encephalopathy; MELD Na, model for end-stage liver disease sodium; SOFA, sequential organ failure assessment score; INR, international normalized ratio; AKI, acute kidney injury; TLC, total leukocyte count; qSOFA, quick SOFA

Mortality Univariate P value Multivariate P value
Age 0.99 (0.97-1.01) 0.54    
Female gender 1.61 (0.73-3.57) 0.23    
Alcohol vs. other etiology 1.28 (0.8-2.04) 0.28    
HE 1.41 (0.9-2.23) 0.13    
MELD Na 1.11 (1.07-1.14) <0.001 1.08 (1.05-1.12) <0.001
H/o norfloxacin prophylaxis 1 (0.58-1.71) 1    
SOFA score 1.15 (1.09-1.21) <0.001 1.06 (1.002-1.12) 0.04
INR 1.06 (0.94-1.21) 0.29    
Bilirubin 1.05 (1.02-1.07) <0.001    
Creatinine 1.21 (1.06-1.4) 0.005    
Albumin 1.03 (0.95-1.11) 0.46    
AKI at admission 2.33 (1.46-3.71) <0.001    
Sodium 0.98 (0.96-1.008) 0.23    
TLC 1 0.002    
Proven infection 2.01 (1.23-3.27) 0.005    
Second infection 1.91 (0.67-5.4) 0.22    
H/o hospitalization 2.2 (1.37-3.52) 0.001    
Resistant organisms vs. nonresistant 1.27 (0.57-2.83) 0.54    
Presence of fever in last 7 days 3.7 (2.12-6.41) <0.001    
qSOFA positive 3.19 (1.98-5.12) <0.001    
Either fever or qSOFA or both 3.45 (2.13-5.6) <0.001 2.19 (1.27-3.76) 0.005