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Mechanical strain modulates myokine secretion. The plots show the secretion of various myokines, insulin‐like growth factor (IGF‐1), myostatin (MSTN), follistatin (FST), follistatin‐like 1 protein (FSTL1), interleukin 6 (IL‐6), and osteonectin (SPARC) in conditioned media of muscle constructs subjected to endurance (END) or high‐intensity interval (HIIT) mechanical stimulation (stretch) compared with their static control. n = 3 for each group.
