Table 3. Anti-inflammatory Activity (% Inhibition) of Hesperidin and Its Metabolites by 5-LOX Evaluation.

	concentration
	10 μg/mL	20 μg/mL	40 μg/mL	p
hesperidin	43.58 ± 4.53b	51.58 ± 3.34ab	61.51 ± 4.01a	0.004
hesperetin	6.25 ± 3.87c	36.01 ± 4.85b	72.88 ± 2.48a	<0.001
naringenin	35.32 ± 6.55b	41.27 ± 1.24ab	51.39 ± 4.14a	0.013
NDGA	54.97 ± 0.10b	84.80 ± 0.17ab	95.12 ± 0.14a	<0.001

^a,

^b,

^c,

There is no difference between groups with the same letter for each measurement value. The data was analyzed by ANOVA Tukey HSD.