Table 1. IC₅₀ Data of Compounds 2a–l and Bortezomib for HL-60, K562, and THP-1 Cells.

		IC50 (μM)
compound	R	HL-60 cell line	K562 cell line	THP-1 cell line
2a	H	149.47	277.84	460.24
2b	4-SO2CH3	149.25	132.60	408.97
2c	4-CH3	98.86	93.54	436.51
2d	4-CN	317.48	198.34	444.94
2e	4-Br	48.02	76.90	301.58
2f	4-F	33.52	57.28	390.68
2g	4-Cl	62.34	50.23	294.42
2h	3-Br	42.89	33.61	481.98
2i	3-Cl	186.32	111.78	339.09
2j	3-F	176.33	363.10	221.35
2k	3-NO2	143.95	141.31	194.69
2l	4-OCH3	321.75	209.13	287.03
Bortezomib		31.75	42.69	108.67