TABLE 1.
Resistance of E. coli mutant strains to coppera
| Relevant genotype | Systems present | MIC (mM) of Cu2+ |
|---|---|---|
| Wild type | All | 3.25 |
| ΔrpoE | CopA, CueO, Cus | 2.75 |
| ΔcopA | RpoE, CueO, Cus | 2.25 |
| ΔcueO::cat | RpoE, CopA, Cus | 3.00 |
| ΔcusCFBA | RpoE, CopA, CueO | 3.25 |
| ΔrpoE ΔcopA | Cus, CueO | 2.00 |
| ΔcopA ΔcueO::cat | RpoE, Cus | 2.25 |
| ΔcopA ΔcusCFBA | RpoE, CueO | 2.25 |
| ΔrpoE ΔcueO::cat | Cus, CopA | 2.50 |
| ΔrpoE ΔcusCFBA | CopA, CueO | 2.25 |
| ΔcusCFBA ΔcueO::cat | RpoE, CopA | 1.25 |
| ΔrpoE ΔcopA ΔcueO::cat | Cus | 2.00 |
| ΔrpoE ΔcopA ΔcusCFBA | CueO | 2.00 |
| ΔrpoE ΔcusCFBA ΔcueO::cat | CopA | 1.00 |
| ΔcopA ΔcusCFBA ΔcueO::cat | RpoE | 1.25 |
| ΔrpoE ΔcopA ΔcusCFBA ΔcueO::cat | None | 1.00 |
a
MICs were determined on LB medium overnight at 37°C. The mean values of three independent experiments with identical results are shown.