Cluster of archaeal-type genes in M. extorquens AM1. Functions of genes shown as grey arrows are known. fhcA, -B, -C, and -D encode the four subunits of the formyltransferase-hydrolase complex (16), mptG encodes ribofuranosylaminobenzene phosphate synthase (18), mtdB encodes methylene-H4MPT dehydrogenase (9), mch encodes methenyl-H4MPT cyclohydrolase (17), and fae encodes formaldehyde-activating enzyme (22). The function of ORFY remains unknown. Functions of genes shown in hatched arrows are assessed in this study. Genes shown as open arrows, as well as mtdB, have no homologs among Archaea.