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. 2023 Sep 4;22(11):e13971. doi: 10.1111/acel.13971

FIGURE 1.

FIGURE 1

Old Pla2r1 knockout (KO) mice display fewer age‐related marks. (a) Intraperitoneal glucose tolerance test and (b) intraperitoneal insulin tolerance test of 14‐month‐old (adult) WT (n = 7) and Pla2r1 KO (n = 8; for a), and 20‐month‐old (old) WT (n = 7) and Pla2r1 KO (n = 8; for a and b) female mice. Mean ± SEM. Multiple Mann–Whitney tests. *p < 0.05, **p < 0.01. (c) Relative telomere length of liver from 3‐month‐old (young) WT (n = 7) and Pla2r1 KO (n = 9) and from 21‐month‐old (old) WT (n = 3) and KO Pla2r1 (n = 5) female mice. Mean ± SEM. Unpaired two‐tailed Student t test. (d) Quantification of relative blood ALP level in WT (n = 4) and Pla2r1 KO (n = 10) 3‐month‐old (young) mice, and WT (n = 4) and Pla2r1 KO (n = 7) 21‐month‐old (old) mice. Mean ± SEM. Unpaired two‐tailed Student t test.