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. 2023 Nov 2;14:1285113. doi: 10.3389/fimmu.2023.1285113
GBM Glioblastomas
WHO The World Health Organization
TMZ Temozolomide
rGBM Recurrent glioblastoma
mOS Median overall survival
OV Oncolytic virus
HSV-1 Herpes simplex virus-1
Ad Adenovirus
NDV Newcastle disease virus
RV Reovirus
oHSV Oncolytic herpes simplex virus
TK Thymidine kinase protein
dNMP Deoxyribonucleotides
PKR Protein kinase R
RR Ribonucleotide reductase
pfu Plaque forming units
GSC Glioblastoma stem cells
pHGG Pediatric high-grade glioma
DIPG Diffuse intrinsic pontine glioma
scFv Single chain fragment variable
TAP The antigen presenting
MHLW Ministry of Health, Labour and Welfare
CRAds Cancer-Selective Replicating Adenoviruses
5-FU 5-fluorouracil
CAR Coxsackie adenovirus receptor
mE1A Mutant E1A
CPT-11 Camptothecin analogue irinotecan
RGD Arginine-glycine aspartic acid
pHGG Pediatric high-grade gliomas
DIPGs Diffuse intrinsic pontine gliomas
vp Viral particles
RT Radiotherapy
4-1BBL 4-1BB ligand
DNX-2440 Delta-24-RGDOX
OX40L OX40 ligand
pRb The retinoblastoma tumor suppressor protein
PVSRIPO Recombinant nonpathogenic polio-rhinovirus chimera
CD Cytosine deaminase
Toca FC Prodrug 5-fluorocytosine
SOC Standard of care
ZIKV Zika virus
GSCs Glioblastoma multiforme stem cells
3’UTR 3’ untranslated region
BBB Blood-brain barrier
TME Tumor microenvironment
CED Convection-enhanced delivery